Acquired pure red cell aplasia.

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Acquired pure red cell aplasia.

Correspondence MEDICALTJOSRNAL 559 Acquired Pure Red Cell Aplasia SIR,-May we make the following observation about your article on acquired pure red cell aplasia and its treatment with steroids (6 April, p. 3) ? A pure red cell aplasia that responded to riboflavine or prednisone has been described in African adults and in children with marasmus and kwashiorkor.' In marasmus and kwashiorkor an e...

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Acquired pure red cell aplasia: updated review of treatment

Pure red cell aplasia (PRCA) is a syndrome characterized by a severe normocytic anaemia, reticulocytopenia, and absence of erythroblasts from an otherwise normal bone marrow. Primary PRCA, or secondary PRCA which has not responded to treatment of the underlying disease, is treated as an immunologically-mediated disease. Although vigorous immunosuppressive treatments induce and maintain remissio...

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Studies on Pure Red Cell Aplasia

An 1 8-yr-old female with chronic active The patient’s plasma was cytotoxic for hepatitis developed a severe anemia due erythroblasts. Following splenectomy, a to a lack of red cell production. Her bane remission of the disease occurred. This marrow showed many large proerythrostudy indicates that in some cases the blasts but an almost complete lack of more anemia associated with abundant marro...

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Azathioprine-induced pure red-cell aplasia.

Long-term administration of azathioprine is widely used to prevent rejection in organ transplantation and in the treatment of autoimmune diseases. Bone marrow toxicity is a well-known side-effect of azathioprine. Macrocytosis, with or without megaloblastic erythropoiesis in the bone marrow, and (mild) leukopenia are frequently seen [1-4]. Less common effects are anaemia, thrombocytopenia and pa...

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Diphenylhydantoin-induced pure red cell aplasia.

Pure red cell aplasia is an uncommon complication of diphenylhydantoin therapy. It has not been reported in Indian literature. Awareness of the entity helps in establishing the cause of anaemia in these patients and alerts the physicians to the need of comprehensive haematological monitoring in these patients. A case of 58-year-old male who developed pure red cell aplasia following three months...

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ژورنال

عنوان ژورنال: BMJ

سال: 1968

ISSN: 0959-8138,1468-5833

DOI: 10.1136/bmj.2.5604.559